[(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(1-azepanylmethylene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Name	Pivmecillinam
Synonyms	Pivmecillinam PIVMECILLINAM PIVAMDINOCILLIN AMDINOCILLIN PIVOXIL [(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(1-azepanylmethylene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate (2S,5β)-6α-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid [2,2-dimethyl-1-oxopropoxy]methyl ester 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)- PIVMECILLINAM IMPURITY CMETHYLENE 2,2-DIMETHYLPROPANOATE (2RS,4S)-2-[[[(HEXAHYDO-1H-AZEPIN-1-YL)METHYLENE]AMINO]METHYL]-5,5-DIMETHYLTHIAZOLIDIN-4-CARBOXYLATE EPP(CRM STANDARD)
CAS	32886-97-8
EINECS	251-276-6

Molecular Formula	C21H33N3O5S
Molar Mass	439.57
Density	1.30±0.1 g/cm3(Predicted)
Melting Point	118-119 C
Boling Point	581.0±60.0 °C(Predicted)
Specific Rotation(α)	D20 +231° (c = 1 in 96% ethanol)
Solubility	DMSO: soluble5mg/mL, clear (warmed)
Appearance	powder
Color	white to beige
pKa	8.11±0.60(Predicted)
Storage Condition	-20°C
Use	Pivmecillinam (FL-1039) is a precursor compound of mecillinam, a broad-spectrum antibiotic.

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
RTECS	XI0185000
Toxicity	LD50 in mice, rats (mg/kg): 475-480, 465 i.v.; 1736-1930, 1935-2100 s.c.; 3020, 9500-10000 orally (Sato)

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